Now this is a scifi MMO to get excited about. In the same issue of Game Informer where BioWare revealed Mass Effect 3, they went on to discuss the future of the franchise after the trilogy ends and naturally a MMO came up. Mass Effect 3 will end the story relating to the Reaper, and Executive Producer Casey Hudson specifically hinted at getting beyond the Reaper storyline and being able to freely explore the universe. Living on the Citadel or taking a ship to Omega were two examples given.
A Mass Effect MMO, set in the same universe after the trilogy of games, would be almost like a sci-fi World of Warcraft. WoW is set in the Warcraft universe following Warcraft 3, so you have established lore and familiarity to play off of. And the Mass Effect universe is one of the best scifi settings in a long time, so we can’t help but get a little excited at the mere possibility of a MMO set there.